Swiss seek progress on U.S. tax deal: economy minister
















ZURICH (Reuters) – Switzerland hopes to restart talks with the U.S. over a long-simmering tax dispute following the re-election of president Obama, its economy minister was quoted as saying on Sunday.


Switzerland is trying to reach a deal to end investigations by U.S. tax authorities into 11 banks, including Credit Suisse and Julius Baer , suspected of helping clients dodge U.S. taxes with the help of offshore bank accounts.













It needs the tax deal so that it can normalize its banking relations with the United States and wants the investigations dropped in return for the payment of hefty fines by the Swiss banks and the transfer of names of thousands of U.S. clients.


“We are seeking clarification quickly,” Johann Schneider-Ammann told the Zentralschweiz am Sonntag newspaper. “The situation has been blocked recently. That must now change.”


The talks had stalled in the run-up to the U.S. election, and finance minister Eveline Widmer-Schlumpf has suggested the ball is firmly in the U.S. court.


The two countries are at odds over U.S. demands for Switzerland to hand over bank data from before 2009.


In a separate interview with the BaslerZeitung at the weekend, Credit Suisse Chairman Urs Rohner said the unresolved tax deal was a burden.


“We are doing everything that we can and may to resolve the problem. But in the end there is a need for a solution that all involved will have to agree to.”


(Reporting by Caroline Copley; Editing by Elaine Hardcastle)


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Israel kills Gaza rocket crewman in second day of clashes
















GAZA (Reuters) – An Israeli air strike killed a Palestinian militant in the Hamas-governed Gaza Strip on Sunday as a surge in cross-border violence entered its second day, local officials said.


Islamic Jihad, a smaller faction than Hamas which often operates independently, identified the dead man as one of its own, saying he was a member of a rocket crew hit by an Israeli missile in Jabalya, northern Gaza.













The Israeli military confirmed carrying out an air strike in the area. The death brought to six the number of Palestinians killed by Israel since four of its troops were hurt in a missile attack on their jeep along the Gaza boundary fence.


Islamic Jihad said it had fired 70 short-range rockets and mortar bombs across the border since Saturday, salvoes which drove Israeli residents to blast shelters. At least one Israeli, in the town of Sderot, was wounded, ambulance workers said.


Israel described the jeep ambush as part of a Palestinian strategy of trying to curb its countermeasures against possible cross-border infiltration. Israeli forces often mount hunts for tunnels and landmines on the inside of the Gaza boundary, creating a no-go zone for Palestinians.


“Of course we don’t accept their attempt to change the rules,” Defence Minister Ehud Barak told Israel’s Army Radio.


“The essence of the struggle is over the fence. We intend to enable the IDF (Israel Defence Forces) to work not just on our side but on the other side as well.”


Palestinians said four of Saturday’s dead were civilians hit by an Israeli tank shell while paying respects at a crowded mourning tent in Gaza’s Shijaia neighborhood. Israel denies targeting civilians.


The bloodshed puts internal pressure on Hamas, which, though hostile to the Jewish state, has sat out some of the recent rounds of violence as it tried to consolidate its Gaza rule and reach out to neighboring Egypt and other foreign powers.


Israel blames Hamas for any attacks emanating from Gaza, but has shown little appetite for a major sweep of the territory which might strain its own fraught ties to the new Islamist-rooted government in Cairo.


(Writing by Dan Williams; Reporting by Nidal al-Mughrabi; Editing by Todd Eastham)


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Philip Roth Is Retiring; Amazon Glitch Disables Buy Buttons
















Today in books and publishing: Philip Roth confirms his retirement; Amazon‘s mysteriously vanishing buy buttons; Kobo expands to Italy, Kindle considers China; cities in literature.


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Philip Roth wraps it up. One of America’s most celebrated living novelists has been hinting at retirement for a while now. But he didn’t choose to make a big announcement in a prominent stateside literary organ like The New York Review of Books. He chose instead to let it out in interviews with the foreign press over recent weeks. Last month he told Nelly Kaprièlian of French magazine Les Inrockuptibles that he hasn’t written new material in three years, and doesn’t plan to write any new novels. “To tell you the truth, I’m done,” he said frankly, “Nemesis will be my last book … Enough is enough! I no longer feel this fanaticism to write that I have experienced in my life.” He said the same thing in an interview with Italian magazine La Repubblica earlier this month. His publisher Houghton Mifflin confirmed that Roth is entering retirement. It looks the 74-year-old writer will have plenty of time to go over his life story and thoughts on literature with his new biographer, Blake Bailey. [Salon]


RELATED: How to Game Amazon Prime; Random House Consolidates in the Spanish Market


Where did Amazon‘s buy buttons go? Late last night, customers looking to replenish their Kindles with fresh e-books were probably quite frustrated. No matter how hard anyone clicked, there was no way to purchase e-books from Penguin, Random House, Macmillan, Simon & Schuster, Hachette, and HarperCollins through Amazon. A company spokesperson later confirmed that it was just a technical slip-up, and buy buttons were quickly restored. But given Amazon’s propensity to punish publishers that don’t bend to its will with disabled buy buttons, this brief black-out set off a minor panic in publishing land. Why were only Big Six publishers affected? Did it have anything to do with the ongoing agency pricing legal battles or the Penguin Random House merger? Though it seems to have been nothing more serious than a technical goof, it’s a stark reminder that Amazon has the ability—as well as the leverage—to shut down publishers’ most important connection with consumers at the click of a mouse. [New York Observer]


RELATED: Chart: The Rapid Gains of the E-book


E-reading takes a global turn. E-books may be taking firm holds in the U.S., but they have a long way to go before they became the global format of choice for readers. Italy may be going in an increasingly digital direction soon, with the country’s largest bookseller Mondadori Group partnering with Kobo to stock Touch e-readers in its hundreds of stores. 34,000 e-books will be available for Italian readers. China is another largely untapped market, one that Amazon is eyeing enviously. ZDNet’s Liau Yun Qing reports that Kindles may become available there as early as this month. “If Amazon brings its e-reader to China, it will face competition from Chinese e-commerce player Dangdang which launched its e-reader in July at a retail price of 599 yuan (US$ 79),” she writes. “In comparison, the cheapest Kindle Paperwhite e-reader, which includes “Special Offers”, retails at US$ 119 in the United States.” [ZDNet]


RELATED: New Batman Comic Postponed; Books Banned in China Thrive in Hong Kong


Cities in literature. Mark Binelli’s new book Detroit City Is the Place to Be is all about the Motor City—its ascent during America’s industrial golden age, and its struggle to redefine itself. Given his obsession with the urban, Publishers Weekly decided to tap Binelli for a list of his favorite books that take specific cities as a central theme. It’s more interesting than most lists on this subject might have been. For instance, he shines a light on Joan Didion not for her classic takes on San Francisco or New York, but for her book Miami. And his favorite books to take on New York—Ben Katchor’s The Jew of New York and Joseph Mitchell’s Up in the Old Hotel—are refreshing inclusions. His favorite book about Detroit, Elmore Leonard’s City Primeval, is also a bit surprising. [Publishers Weekly]


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Weinstein Co., Clear Channel, Madison Square Garden Hosting Benefit Concert for Sandy Relief
















LOS ANGELES (TheWrap.com) – Clear Channel Media, The Madison Square Garden Company and The Weinstein Company are joining together to produce a benefit concert to raise money for victims of Hurricane Sandy.


The concert, titled “12-12-12,” will feature live music, although the producers did not reveal who would be performing. The roster should be an A-list one though, given that this is the same group of corporate entities that backed “The Concert for New York City,” a star-studded affair with the likes of The Who and Billy Joel on hand to raise money for 9/11.













The concert for Sandy Relief will be held on December 12, 2012, at Madison Square Garden in New York, and the money raised will be dispensed through the Robin Hood Relief Fund.


Hurricane Sandy slammed into the Eastern Seaboard last week, leaving 110 people dead and more than 1 million without power. Damage from the storm is estimated to be between $ 30 billion to $ 50 billion in economic losses.


“12-12-12″ will be produced by James Dolan, executive chairman of The Madison Square Garden Company; John Sykes, president of Clear Channel Entertainment Enterprises; and Harvey Weinstein, co-founder and chairman of The Weinstein Company.


In a joint statement, the producers said: “The Concert for New York City was a night filled with emotion, courage and tremendous hope when we came together as a city following the 9/11 attack. Once again, our city, as well as millions of our neighbors in the tri-state area, are in desperate need of our assistance as they recover from Hurricane Sandy and rebuild their lives. We have no doubt that the event we are planning will be filled with unforgettable music, entertainment and that uniquely American spirit of community, compassion and generosity.”


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Abbott hepatitis C drugs bring high cure rates in trial
















(Reuters) – A trio of oral medicines from Abbott Laboratories Inc to treat hepatitis C produced unprecedented cure rates in patients who had failed to benefit from standard treatment, as well as very high cure rates for newly treated patients, Abbott said on Saturday.


Detailed data from the mid-stage trial, called Aviator, were released Saturday at the annual meeting of the American Association for the Study of Liver Disease (AASLD) in Boston.













Investors and patients have very high hopes for the Abbott drugs – a protease inhibitor called ABT-450, a polymerase inhibitor ABT-333 and ABT-267 from a class known as NS5A inhibitors. They are used without interferon, an injectable standard treatment that causes flu-like symptoms.


Abbott said it plans to move ahead with large Phase III studies of the three drugs, used either with or without the standard antiviral pill ribavirin, based on favorable results seen in patients treated for eight weeks or twelve weeks in the Aviator study. Patients in the study had the most common, and hardest-to-treat, strain of hepatitis C known as Genotype 1.


Some 93 percent of patients who failed prior therapy had a sustained virologic response (SVR), meaning they were considered cured, after 12 weeks of taking the trio of new drugs, plus ribavirin.


“Nobody anywhere has broken the 50 percent mark in (cure rates) for this population,” Scott Brun, a senior Abbott research executive said in an interview. “These are robust results.”


Abbott said it aims to be the first company to market an interferon-free regimen to patients with Genotype 1 infections.


Four of 448 patients in the study discontinued treatment due to adverse events, a dropout rate that Abbott said suggested the medicines were very well tolerated.


About 97 percent of previously untreated patients were considered cured after 12 weeks of treatment with the three Abbott drugs, plus ribavirin. Moreover, similarly impressive cure rates were seen among patients taking the three drugs, plus ribavirin, for 8 weeks.


Without ribavirin, 87 percent of previously untreated patients were considered cured after 12 weeks on Abbott’s three drugs, Abbott said.


A pair of new hepatitis C drugs approved last year, Vertex Pharmaceuticals Inc’s Incivek and Merck & Co’s Victrelis, significantly boosted cure rates and cut treatment duration to as low as 24 weeks for some patients. But the protease inhibitors must still be taken with interferon, an injected drug that often causes severe flu-like symptoms that lead many hepatitis patients to delay or discontinue treatment.


Gilead Sciences Inc, Bristol-Myers Squibb Co and Vertex are racing to develop interferon-free treatment regimens. They are expected to become blockbuster products, if approved, because of their far shorter treatment times and better cure rates, compared with existing drug regimens.


Many analysts view Gilead as current leader both on timing and perceived advantages of its experimental hepatitis C program.


An estimated 3 million Americans are believed infected with the virus, which quietly damages the liver over years or decades and is the biggest reason for liver transplants in the United States. Abbott said as many as 170 million people worldwide are infected.


(Reporting By Ransdell Pierson; Editing by Vicki Allen)


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Czech PM Necas: Soften austerity drive to help economy – paper
















PRAGUE (Reuters) – The Czech government must change tack to help the economy out of a recession and “stop scaring” the public with further budget tightening, Prime Minister Petr Necas was quoted as saying on Saturday.


Pressure has been building on his centre-right cabinet to ease its austerity zeal after the economy slid into a recession and Necas’s Civic Democrats suffered a drubbing in regional and Senate election last month as voters punished them for spending cuts and sleaze scandals.













“We have to stop all the scaring of people and show them a light at the end of the tunnel,” daily Mlada Fronta Dnes quoted Necas as saying.


He said the government should back off from pursuing tough deficit targets while the economy remains weak.


This is the first time Necas has said the cabinet must alter its policy focused primarily on trimming debt, although he stopped short of admitting what many economists have said, that the government’s stubborn fiscal cuts significantly contributed to the three-quarters old economic recession.


Government spokesman Jakub Stadler said the remarks were Necas’s personal opinion which he will discuss with the rest of the government and it was not yet decided what the new deficit targets will be.


The Czech central bank cut its main policy rate to near zero to spur spending and central banker Pavel Rezabek took a rare swipe at the government in a Reuters interview last month, saying it should stop undermining the bank’s efforts to drag the economy out of recession.


Necas said poor demand was a “psychological matter”, meaning people and businesses constantly hearing of plans for budget cuts and economic crisis in the euro zone prefer to stash money in their bank accounts in anticipation of bad times ahead rather than spend and invest.


“Ministers should not longer scare people but they should give them hope… because the government’s consolidation effort has brought results,” the paper quoted him as saying.


He said what the economy needed now was a slowdown in the government’s fiscal consolidation efforts.


The government will now ease off on its plans to cut the public sector deficit, after it has managed to slash it significantly to 3.3 percent of gross domestic product (GDP) last year from 5.8 percent in 2009, he said.


While it had been planning to trim the gap further to 2.9 percent of GDP in 2013 from an expected 3.2 percent this year, and to 2.5 percent in 2014 and 1.6 percent in 2015, Necas told the paper the government should now make do with keeping the deficit below 3 percent in those years.


“When economic growth is at around 2 percent, it will again possible to return to lowering budget deficits,” the paper quoted him as saying.


Necas’s fragile coalition government warded off collapse last week, surviving a vote of confidence after quelling a rebellion among Necas’s Civic Democrats against another series of tax hikes that it pushed through the lower house.


Two years of concerted effort by the administration to reduce debt has helped Czechs cut bond yields, or costs the country pays for borrowing money, to record lows.


The yield on the ten-year paper was 1.908/810 on Friday below levels of many euro zone member states, including for example Belgium’s 2.342/268 on a corresponding bond.


But it has made Necas’s cabinet extremely unpopular and his Civic Democrats suffered a bitter defeat in both regional and Senate elections last month.


The austerity drive also took its toll on economic growth as a plunge in government and household consumption caused the economy to contract every quarter since the final three months of 2011, while others in the region, such as neighboring Poland and Austria, grew.


(Reporting by Jana Mlcochova; Editing by Toby Chopra)


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Twin explosions strike southern Syrian city
















BEIRUT (AP) — Syria‘s state-run news agency says two large explosions have struck the southern city of Daraa, causing multiple casualties and heavy material damage.


SANA did not immediately give further information or say what the target of Saturday’s explosions was.













The Britain-based Syrian Observatory for Human Rights says the blasts went off near a branch of the country’s Military Intelligence in Daraa.


The Observatory, which relies on a network of activists on the ground, says the explosions were followed by clashes between regime forces and rebels fighting to topple President Bashar Assad.


Middle East News Headlines – Yahoo! News



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‘NBA 2K13′ tops video games titles in October
















NEW YORK (AP) — U.S. retail sales of new video game hardware, software and accessories fell 25 percent in October, marking the 11th straight month of declining sales for physical game products, according to a report from NPD Group.


Many gamers are waiting for big holiday releases such as Activision‘s “Call of Duty: Black Ops II.”













NPD said sales fell to $ 755.5 million from $ 1 billion a year earlier. Sales of video games themselves, excluding PC titles, fell 25 percent to $ 432.6 million. Sales of hardware such as Microsoft‘s Xbox 360 fell 37 percent to $ 187.3 million. Sales of accessories, meanwhile, grew 5 percent to $ 135.6 million.


Thursday’s study from NPD Group tracks sales of new physical products — about 50 percent of the total spending. Excluded are sales of used games and rentals as well as digital and social-network spending.


NPD also listed the top-selling games in October:


1. “NBA 2K13,” Take-Two Interactive Software Inc.


2. “Resident Evil 6,” Capcom USA


3. “Pokemon Black Version 2,” Nintendo Co.


4. “Dishonored,” Bethesda Softworks


5. “Pokemon White Version 2,” Nintendo Co.


6. “Madden NFL 13,” Electronic Arts Inc.


7. “FIFA Soccer 13,” Electronic Arts Inc.


8. “Medal of Honor: Warfighter,” Electronic Arts Inc.


9. “Borderlands 2,” Take-Two Interactive Software Inc.


10. “Skylander Giants,” Activision Blizzard Inc.


Gaming News Headlines – Yahoo! News



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Tiny Tick May Be Spreading Vegetarianism
















A tiny tick might be to blame for a rash of meat allergies in central and southern regions of the U.S.


A bite from the lone star tick, so-called for the white spot on its back, looks innocent enough. But researchers say saliva that sneaks into the wound might trigger a reaction to meat agonizing enough to convert lifelong carnivores into wary vegetarians.













“People will eat beef and then anywhere from three to six hours later start having a reaction; anything from hives to full-blown anaphylactic shock,” said Dr. Scott Commins, assistant professor of medicine at the University of Virginia in Charlottesville. “Most people want to avoid having the reaction, so they try to stay away from the food that triggers it.”


Cases of the bizarre allergy are cropping up in areas ripe with lone star ticks, according to research presented today at the American College of Allergy, Asthma and Immunology annual meeting in Anaheim, Calif. But whether the bugs cause meat allergies remains unclear.


“It’s hard to prove,” said Commins. “We’re still searching for the mechanism.”


Allergies are immune reactions to foreign substances, from pet hair to peanuts. As antibodies attack the substance that caused the reaction, they trigger the release of histamine, a chemical that causes hives and, in severe cases, life-threatening anaphylaxis.


Commins said blood levels of antibodies for alpha-gal, a sugar found in beef, lamb and pork, rise after a single bite from the lone star tick. He said he hopes experiments that combine tiny samples of tick saliva with the invisible antibodies will prove the two are directly connected.


“It’s complicated, no doubt,” said Commins. “But we think it’s something in the saliva.”


The long lag between exposure to meat and the allergic reaction complicates things even more.


“Most food allergies occur very quickly,” said Dr. Stanley Fineman, president of the American College of Allergy, Asthma and Immunology. “It’s also a bit unusual to see adults develop a food allergy.”


But the tick bite theory could help explain the sudden onset of some meat allergies, Fineman added.


Other Common food allergens include peanuts, shellfish, milk, eggs, soy and wheat. And most food allergy sufferers are glad to discover the source of their misery, even if it means upheaval for their diets.


“Avoidance is the best way to handle any food allergy,” he said.


But meat allergies are hard for some brawny barbecuers to swallow.


“Some people are totally destroyed,” said Commins. “Others say, ‘Maybe I’m better off without it.’”


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Administrator cuts 330 Comet jobs

















The joint administrators of Comet say 330 staff are being made redundant.













The cuts will be made at the retailer’s head office and support centres in Rickmansworth (99), Hull (53) and a call centre in Clevedon (42).


There have been no redundancies at Comet distribution centres or stores, which continue to trade as normal and no further redundancies are planned.


All 236 Comet stores continue to trade as normal, and staff will continue to be paid, administrators say.


Administrator Neville Kahn said: “Staff will continue to be paid for the work they do while Comet is trading in administration. We remain extremely grateful to the staff and management for their continued loyalty and support at what is clearly a very difficult time.”


All employees who have been made redundant will be receiving full wages earned during the administration. The administrators will also provide assistance in claiming payments from the government’s Redundancy Payments Office.


Comet’s future


Joint administrators Neville Kahn, Nick Edwards and Chris Farrington, from the business advisory firm Deloitte, were appointed last Friday to oversee a possible revival of Comet or sale of the business.


“We are in discussions with a number of parties who have expressed interest in parts of the business and we continue to work hard to preserve jobs,” said Mr Kahn.


He added: “An in-store sale across all stores commenced yesterday and will continue through the coming weeks. We are pleased with the response so far, as the discounts have helped generate record levels of sales.”


It is reported that rival electrical retailers Dixons and PC World enjoyed a surge in shoppers last weekend after Comet called in administrators.


Comet was forced into adminstration after its US backers pulled the plug.


OpCapita and its founder Henry Jackson agreed a deal to buy Comet from Kesa last year for just £2. The private equity advisory firm has been under fire from critics for allowing the retailer to collapse.


BBC News – Business



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